CRISPR Functional Genomics is a national, SciLifeLab-funded infrastructure based in Biomedicum 9B, Solna.

CFG offers state-of-the-art CRISPR-based functional genomic techniques

• Genome-wide or custom CRISPR-KO / CRISPR-inhibition screens for loss-of-function studies
• Genome-wide or custom CRISPR-activation screens for gain-of-function studies
• Targeted CRISPR-screens with single cell transcriptomic readout
• Design, creation and screening of any custom guide-libraries up to 200,000 guides

 and flexible CRISPR-based precision gene editing

• Gene knock-out, knock-ins of reporters and tags into endogenous loci
• Small mutations (point mutations, insertions, deletions)
• Strategy and reagent design for CRISPR transgenic mice
• Base-editing, prime-editing
• Genotyping support

CFG is open to the entire Swedish research community.

Leadership

Bernhard Schmierer PhD | Director
Email: bernhard.schmierer@ki.se

Links and Resources

• Website at Karolinska Institutet
• Website at SciLifeLab

Contacts

Map